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  1. #1
    Frogger's Avatar
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    What is the difference between Xanax and Ativan?

    Are they about the same kind of drug? Which is better for anxiety and why?

  2. #2
    PurpleRose's Avatar
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    hey there
    well they are in the same family of anti anxiety drugs known as Benzodiazipines, wonderful drugs in my opinion but addictive however Xanax is more potent than lorazepam but both Xanax and lorazepam or Ativan as its also known are fast acting, usually within 20-30mins whereas the potent klonopin/clonazepam takes longer to work but stays in your system longer as does the weakest one Diazepam/Valium the most commonly used anti anxiety drug because its weaker and easier to ween off, however Xanax is twice as potent as lorazepam and ten times as potent as diazepam
    there are many equivalency charts, i should go and find one and post it

    so 0.5mg of Xanax is the same as 1mg of ativan and both are the equivalent to 10mg of valium/diazepam
    Xanax and klonopin are both the same in strength but Xanax has the edge in a lot of ways because it works quicker and still lasts, whereas klonopin is really hard to come off of and takes a good two hours to kick in, i speak from experience.

  3. #3
    metamorphosis's Avatar
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    Here is a benzodiazepine comparison chart. It shows the half-lives and dosage conversion for all of the benzos. the two you were interested in are highlighted.
    Alprazolam (Xanax) has a half-life of 6-12 hrs. It's potency is shown at .5mg
    The next on your list is
    Lorazepam
    (Ativan). It's half-life is 10-20 hrs and it's equivalent potency is 1mg.
    So, Ativan has about a 8 hr longer half life. Meaning the peak plasma levels will go up slower but will be maintained for a longer period of time.
    Xanax, is probably the #1 prescribed benzo. for panic attacks. Because it has a shorter half-life. So peak plasma levels are going to be reached and felt more quickly, and than it's levels drop quickly. Xanax is twice as potent at a two to one ratio.

    Now, as far as why some are used more for SA or anxiety disorder in general. While some are used for acute panic attacks. Well, it all comes down to the half-life of each med. The longer acting benzos., but no less stronger or weaker than another benzodiazepine. To say that is a misnomer. Some ,like clonazepam have a long half-life of 45-48hrs and so it suits the needs of SA and GAD anxiety types more. Another, is diazepam, which even though it may take 2- 10mg tabs to equal the one 1mg tab of clonazepam. Does that make it a weaker drug. maybe on surface value, but realize this. that the Valium half-life is a whopping 100+hrs. So, to say that you can take 2mg of this "stronger"'med which lasts for 4hrs or you can take 20mg of a slower, but still potent benzo with a 100 hr half-life is not relevant. You can see their strengths and weaknesses for what they are( slow acting or fast acting). One last thing about the longer acting benzos. they are often used, as is the case of diazepam, to come of the addiction or tolerance built to a quicker acting Xanax or Ativan or Tamezapam. This is simply for the fact that if you want to titrate down using another longer acting benzo. as a buffer. than diazepam is #1 for this because of it's long half-life. The longer the plasma levels stay up in your body and slowly decline. the easier the taper going to be. Thats why in extreme , high dosage tolerance many will use the taper method with valium because it sticks around and once rid of the original faster acting benzo. The reduction of diazepam goes rather smoothly.

    So, finally the two mentioned. first off with all of my years either listening to others tell it or from first hand benzo. experience with Klonopin, Valium, Xanax, and Ativan. If you were to separate the longer acting, (30+hrs) and the shorter acting, (4-25)hrs. into the two distinguishable groups. You will have one person whose physiological nad psychological make-up will say Xanax saves me from panic attacks. while you will have others that prefer Ativan. It's the same with the long- acting benzos. I really get tired on valium. I know others that prefer Valium and it's longer half-life over Klonopin, which does not make me tired. This isn't even factoring in many benzos. on that list. Just the ones that are more prescribed

    Here are some links on the two and comparisons:

    http://www.drugs.com/forum/featured-...nax-53408.html

    http://www.healthboards.com/boards/anxiety/356263-xanax-vs-klonopin-vs-ativan.html

    http://www.differencebetween.info/difference-between-xanax-and-ativan

    http://www.askapatient.com/comparedrugs.asp?class=ANTIANXIETY

    http://www.askapatient.com/viewrating.asp?drug=17794&name=ATIVAN

    http://www.askapatient.com/viewrating.asp?drug=18276&name=XANAX

    http://en.wikipedia.org/wiki/List_of_benzodiazepines

    http://web4health.info/en/answers/bi...o-overview.htm





    BENZODIAZEPINE EQUIVALENCE TABLE
    (Benzodiazepine Equivalency Table)
    Revised April 2007
    This Benzodiazepine Equivalence Table is based on the extensive research and clinical experience of Professor C Heather Ashton, DM, FRCP, Emeritus Professor of Clinical Psychopharmacology at the University of Newcastle upon Tyne, England. Sources: NRHA Drug Newsletter, April 1985 and Benzodiazepines: How they Work & How to Withdraw (The Ashton Manual), 2002. The approximate equivalent doses to 10mg diazepam (Valium) are given.
    For a discussion of half-lives and equivalencies see also the Benzo FAQ document.
    Benzodiazepines1 Half-life (hrs)2
    [active metabolite]
    Approximately Equivalent
    Oral dosages (mg)3
    Market Aim4
    Alprazolam
    (Xanax, Xanor, Tafil)
    6-12 0.5 a
    Bromazepam
    (Lexotan, Lexomil)
    10-20 5-6 a
    Chlordiazepoxide
    (Librium)
    5-30 [36-200] 25 a
    Clobazam
    (Frisium)5
    12-60 20 a,e
    Clonazepam
    (Klonopin, Rivotril)5
    18-50 0.5 a,e
    Clorazepate
    (Tranxene)
    [36-200] 15 a
    Diazepam
    (Valium)
    20-100 [36-200] 10 a
    Estazolam
    (ProSom, Nuctalon)
    10-24 1-2 h
    Flunitrazepam
    (Rohypnol)
    18-26 [36-200] 1 h
    Flurazepam
    (Dalmane)
    [40-250] 15-30 h
    Halazepam
    (Paxipam)
    [30-100] 20 a
    Ketazolam
    (Anxon)
    30-100 [36-200] 15-30 a
    Loprazolam
    (Dormonoct)
    6-12 1-2 h
    Lorazepam
    (Ativan, Temesta, Tavor)
    10-20 1 a
    Lormetazepam
    (Noctamid)
    10-12 1-2 h
    Medazepam
    (Nobrium)
    36-200 10 a
    Nitrazepam
    (Mogadon)
    15-38 10 h
    Nordazepam
    (Nordaz, Calmday)
    36-200 10 a
    Oxazepam
    (Serax, Serenid,
    Serepax, Seresta)
    4-15 20 a
    Prazepam
    (Centrax, Lysanxia)
    [36-200] 10-20 a
    Quazepam (Doral) 25-100 20 h
    Temazepam
    (Restoril, Normison,
    Euhypnos)
    8-22 20 h
    Triazolam
    (Halcion)
    2 0.5 h
    Non-benzodiazepines
    with similar effects 1
    , 6
    Zaleplon
    (Sonata)
    2 20 h
    Zolpidem
    (Ambien, Stilnoct, Stilnox)
    2 20 h
    Zopiclone
    (Zimovane, Imovane)
    5-6 15 h
    Eszopiclone
    (Lunesta)
    6
    (9 in elderly)
    3 h

  4. #4
    PurpleRose's Avatar
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    hey metamorphosis good to see u xx

  5. #5
    UltraShy's Avatar
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    Quote metamorphosis View Post
    Xanax, is probably the #1 prescribed benzo.
    In the US it ranks #1 among benzos, and is the 11th most common prescription out of all meds.

    As for the original question, Xanax & Ativan are much the same. It's a matter of personal preference. I know a woman who hates Xanax, but loves Ativan. They should be so close as to be interchangeable though she has a clear preference. I prefer Xanax, though I don't recall any great difference. Though last time I took any Ativan was 2005. Xanax I took within the last day.

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