Pristiq is approved by the US Food and Drug Administration to treat the following disorders:
  • Major depressive disorder

In addition it is commonly used 'off-label' (which means that it is not formally approved by the US FDA but has shown good anecdotal efficacy in treating the disorder) for the following disorders:
  • Fibromyalgia
  • Generalized anxiety disorder (GAD)
  • Social anxiety disorder (social phobia)
  • Panic disorder
  • Posttraumatic stress disorder (PTSD)